The ADAMTS18 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Adamts18. This antibody recognizes Human, and Mouse antigen. The ADAMTS18 Antibody has been validated for the following applications: Western Blot.
Description
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.Cal S., Gene 283:49-62(2002) [PubMed: 11867212].Martin J., Nature 432:988-994(2004) [PubMed: 15616553].Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039]